ARHGEF25/GEFT Antikörper (C-Term)

Produktnummer ABIN406353

Produktdetails anti-ARHGEF25/GEFT Antikörper

Target: ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

Bindungsspezifität: C-Term

Reaktivität: Ratte, Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF25/GEFT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RLGDQAQGST HTPINGSLPS LLLSPKGEVA RALLPLDKQA LGDIPQAPHD

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GEFT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GEFT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 580 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGEF25/GEFT

Target: ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

Andere Bezeichnung: GEFT (ARHGEF25 Produkte)

Hintergrund: The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).[supplied by OMIM].
Alias Symbols: p63RhoGEF, GEFT
Protein Interaction Partner: PRKCG, RAC1, RHOA, CDC42,
Protein Size: 580

Molekulargewicht: 64 kDa

Gen-ID: 115557

NCBI Accession: NM_182947, NP_891992

UniProt: Q86VW2