STAMBP Antikörper (N-Term)

Produktnummer ABIN406361

Produktdetails anti-STAMBP Antikörper

Target: STAMBP (STAM Binding Protein (STAMBP))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAMBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SDHGDVSLPP EDRVRALSQL GSAVEVNEDI PPRRYFRSGV EIIRMASIYS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against STAMBP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STAMBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 424 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STAMBP

Target: STAMBP (STAM Binding Protein (STAMBP))

Andere Bezeichnung: STAMBP (STAMBP Produkte)

Hintergrund: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: AMSH, MGC126516, MGC126518
Protein Interaction Partner: CHMP1B, CHMP3, GRB2, UBC, TNFRSF1A, GJA1, MAP3K2, VAMP8, SUMO1, NEDD8, CLTC, FDPS, STAM, STAM2, GRAP2, TRIP13, SPG7, CHMP1A, ITGA5, CYP2C9, NTPCR, CHMP5, SMAD7, SMAD6, PJA1, USP28, USP21, CHMP4B, AMN, CTNNBL1, UACA, CHMP4A, MAP2K5, ALAS1, CASR, UBE2S, TRA
Protein Size: 424

Molekulargewicht: 48 kDa

Gen-ID: 10617

NCBI Accession: NM_213622, NP_998787

UniProt: O95630