CDKN3 Antikörper (C-Term)

Produktnummer ABIN311609

Produktdetails anti-CDKN3 Antikörper

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CDKN3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDKN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 212 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDKN3

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Andere Bezeichnung: CDKN3 (CDKN3 Produkte)

Hintergrund: CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDI1, CIP2, FLJ25787, KAP, KAP1, MGC70625
Protein Interaction Partner: CDK2, UBC, NCOA3, MS4A3, CDKN3, CDK3, CDC25A, CDK1, CEBPA,
Protein Size: 212

Molekulargewicht: 23 kDa

Gen-ID: 1033

NCBI Accession: NM_005192, NP_005183

UniProt: Q16667