TUBA3C Antikörper (N-Term)

Produktnummer ABIN311613

Produktdetails anti-TUBA3C Antikörper

Target: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBA3C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VDLEPTVVDE VRTGTYRQLF HPEQLITGKE DAANNYARGH YTIGKEIVDL

Homologie: Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TUBA3C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TUBA3C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 450 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TUBA3C

Target: TUBA3C (Tubulin, Alpha, 3C (TUBA3C))

Andere Bezeichnung: TUBA3C (TUBA3C Produkte)

Hintergrund: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TUBA2, bA408E5.3, TUBA3D
Protein Interaction Partner: CEP70, UBC, MDM2, CD81, K3, UBL4A, DYNLT1, TSGA10, CUL3, ARRB2, ARRB1, VHL, YWHAQ, DYRK2, YWHAZ, YWHAG, YWHAB, PPP4C, PFDN5, GRM7, NMI, PXN, SIAH1, DYNLL1, TUBG1, MYC, FYN, FBL,
Protein Size: 450

Molekulargewicht: 50 kDa

Gen-ID: 7278

NCBI Accession: NM_006001, NP_005992

UniProt: Q13748

Pathways: Microtubule Dynamics