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SPAG6 Antikörper (Middle Region)

SPAG6 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785513
  • Target Alle SPAG6 Antikörper anzeigen
    SPAG6 (Sperm Associated Antigen 6 (SPAG6))
    Bindungsspezifität
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 24
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen
    Wirt
    • 35
    • 4
    Kaninchen
    Klonalität
    • 36
    • 3
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPAG6 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 13
    • 13
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    HVVGQFSKVL PHDSKARRLF VTSGGLKKVQ EIKAEPGSLL QEYINSINSC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SPAG6. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SPAG6
    Top Product
    Discover our top product SPAG6 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 509 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • Target
    SPAG6 (Sperm Associated Antigen 6 (SPAG6))
    Andere Bezeichnung
    SPAG6 (SPAG6 Produkte)
    Synonyme
    Repro-SA-1 antikoerper, pf16 antikoerper, PF16 antikoerper, RGD1310892 antikoerper, zgc:91805 antikoerper, SPAG6 antikoerper, repro-sa-1 antikoerper, DKFZp459D035 antikoerper, sperm associated antigen 6 antikoerper, sperm associated antigen 6-like antikoerper, sperm associated antigen 6 L homeolog antikoerper, SPAG6 antikoerper, Spag6l antikoerper, Spag6 antikoerper, spag6 antikoerper, spag6.L antikoerper
    Hintergrund
    SPAG6 is important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
    Alias Symbols: DKFZp434I153, MGC26276, Repro-SA-1, pf16
    Protein Interaction Partner: APP, SPAG16,
    Protein Size: 509
    Molekulargewicht
    56 kDa
    Gen-ID
    9576
    NCBI Accession
    NM_012443, NP_036575
    UniProt
    O75602
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