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MLF1 Antikörper (N-Term)

MLF1 Reaktivität: Human, Maus, Ratte, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785560
  • Target Alle MLF1 Antikörper anzeigen
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Bindungsspezifität
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Kaninchen
    Wirt
    • 61
    • 5
    Kaninchen
    Klonalität
    • 63
    • 3
    Polyklonal
    Konjugat
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MLF1 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 21
    • 20
    • 16
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequenz
    GRDLLSISDG RGRAHNRRGH NDGEDSLTHT DVSSFQTMDQ MVSNMRNYMQ
    Homologie
    Human: 100%, Mouse: 79%, Rabbit: 90%, Rat: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MLF1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human MLF1
    Top Product
    Discover our top product MLF1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 268 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Li, Wu, Jiang, Liu, Wu, Inagaki, Izawa, Mizisin, Engvall, Shelton: "Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice." in: Journal of the neurological sciences, Vol. 264, Issue 1-2, pp. 77-86, (2007) (PubMed).

  • Target
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Andere Bezeichnung
    MLF1 (MLF1 Produkte)
    Hintergrund
    MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
    Alias Symbols: -
    Protein Interaction Partner: CENPU, COPS3, UBC, NRBP1, YWHAZ, GRIK5, MAGEA11,
    Protein Size: 268
    Molekulargewicht
    29 kDa
    Gen-ID
    4291
    NCBI Accession
    NM_022443, NP_071888
    UniProt
    P58340
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