FBXO31 Antikörper (Middle Region)
-
- Target Alle FBXO31 Antikörper anzeigen
- FBXO31 (F-Box Protein 31 (FBXO31))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FBXO31 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FBXO31. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
- Top Product
- Discover our top product FBXO31 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 367 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- FBXO31 (F-Box Protein 31 (FBXO31))
- Andere Bezeichnung
- FBXO31 (FBXO31 Produkte)
- Synonyme
- 1110003O08Rik antikoerper, 2310046N15Rik antikoerper, Fbx14 antikoerper, Fbxo14 antikoerper, FBX14 antikoerper, FBXO14 antikoerper, Fbx31 antikoerper, pp2386 antikoerper, RGD1561069 antikoerper, fbx14 antikoerper, fbx31 antikoerper, fbxo14 antikoerper, fbxo31 antikoerper, F-box protein 31 antikoerper, F-box protein 31 S homeolog antikoerper, F-box protein 31 L homeolog antikoerper, Fbxo31 antikoerper, FBXO31 antikoerper, fbxo31 antikoerper, fbxo31.S antikoerper, fbxo31.L antikoerper
- Hintergrund
-
FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CDT1, UBE2L6, UBE2D1, CCND1, CUL1, MAP2K6, PARD6A, SKP1, COPS5, RBX1,
Protein Size: 367 - Molekulargewicht
- 40 kDa
- Gen-ID
- 79791
- NCBI Accession
- NM_024735, NP_079011
- UniProt
- Q5XUX0
-