PRKAA1 Antikörper (N-Term)
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- Target Alle PRKAA1 Antikörper anzeigen
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRKAA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- GELFDYICKN GRKSDVPGVV KTGSTKELDE KESRRLFQQI LSGVDYCHRH
- Homologie
- Human: 100%, Rabbit: 85%, Rat: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PRKAA1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRKAA1
- Top Product
- Discover our top product PRKAA1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 565 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- Andere Bezeichnung
- PRKAA1 (PRKAA1 Produkte)
- Synonyme
- AMPK antikoerper, AMPKa1 antikoerper, cb116 antikoerper, im:7154392 antikoerper, sb:cb130 antikoerper, wu:fa94c10 antikoerper, AMPK1 antikoerper, AMPKalpha1 antikoerper, AI194361 antikoerper, AI450832 antikoerper, AL024255 antikoerper, C130083N04Rik antikoerper, ampk antikoerper, ampka1 antikoerper, PRKAA1 antikoerper, protein kinase AMP-activated catalytic subunit alpha 1 antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antikoerper, PRKAA1 antikoerper, prkaa1 antikoerper, Prkaa1 antikoerper, prkaa1.L antikoerper
- Hintergrund
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PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: AMPK, AMPKa1, MGC33776, MGC57364
Protein Interaction Partner: PRKAG1, PRKAB2, PRKAB1, GOLGA2, PHC2, CTBP1, CDX4, AES, Trp53, INO80E, RFX6, TRIM27, KRT40, SSX2IP, PNMA5, UBXN11, RIMBP3, L3MBTL3, TSC22D4, VPS37B, HMBOX1, HOMEZ, THAP1, ROPN1, RAD54B, MTUS2, IKZF3, RBPMS, ABI2, ZBED1, BHLHE40, TRIP6, STK11, VPS52, PPARG
Protein Size: 565 - Molekulargewicht
- 62 kDa
- Gen-ID
- 5562
- NCBI Accession
- NM_206907, NP_996790
- UniProt
- Q13131
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
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