SQSTM1 Antikörper (Middle Region)
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- Target Alle SQSTM1 Antikörper anzeigen
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schaf, Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SQSTM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- EEQMESDNCS GGDDDWTHLS SKEVDPSTGE LQSLQMPESE GPSSLDPSQE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SQSTM1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SQSTM1
- Top Product
- Discover our top product SQSTM1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 440 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Andere Bezeichnung
- SQSTM1 (SQSTM1 Produkte)
- Synonyme
- SQSTM1 antikoerper, sqstm1 antikoerper, MGC79491 antikoerper, A170 antikoerper, OSIL antikoerper, PDB3 antikoerper, ZIP3 antikoerper, p60 antikoerper, p62 antikoerper, p62B antikoerper, OSF-6 antikoerper, Osi antikoerper, STAP antikoerper, ZIP antikoerper, sb:cb621 antikoerper, zgc:85784 antikoerper, sequestosome 1 antikoerper, sequestosome 1 L homeolog antikoerper, SQSTM1 antikoerper, sqstm1 antikoerper, Sqstm1 antikoerper, sqstm1.L antikoerper
- Hintergrund
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This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to m
Alias Symbols: A170, OSIL, PDB3, ZIP3, p60, p62, p62B
Protein Interaction Partner: HTT, BCL2, ATXN3, MAP1LC3A, tat, GABARAPL1, GABARAPL2, KEAP1, SQSTM1, UBC, TP53, TRIM63, TRIM55, MAP1LC3B, TOLLIP, ULK1, GABARAP, OPTN, SESN2, SUMO3, NBR1, EPAS1, EGLN3, CFTR, DCP2, MGRN1, NEDD8, EDEM1, LGALS3, IKBKG, TNK2, DVL2, FLNB, PSMD12, PSMD10, PSM
Protein Size: 440 - Molekulargewicht
- 48 kDa
- Gen-ID
- 8878
- NCBI Accession
- NM_003900, NP_003891
- UniProt
- Q13501
- Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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