ATG10 Antikörper (C-Term)

Produktnummer ABIN311671

Produktdetails anti-ATG10 Antikörper

Target: ATG10 (Autophagy Related 10 (ATG10))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TPVLKNSQKI NKNVNYITSW LSIVGPVVGL NLPLSYAKAT SQDERNVP

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ATG10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG10

Target: ATG10 (Autophagy Related 10 (ATG10))

Andere Bezeichnung: ATG10 (ATG10 Produkte)

Hintergrund: Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form.Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM].
Alias Symbols: APG10, APG10L, DKFZP586I0418, FLJ13954, pp12616
Protein Interaction Partner: ATG3, ATG4B, ATG7, HAT1, USP11, USP7, RBBP7, MAP1B, KRT85, ADSS, ATG5, ATG12,
Protein Size: 220

Molekulargewicht: 25 kDa

Gen-ID: 83734

NCBI Accession: NM_031482, NP_113670

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagie