JAK3 Antikörper (N-Term)
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- Target Alle JAK3 Antikörper anzeigen
- JAK3 (Janus Kinase 3 (JAK3))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser JAK3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- APPSEETPLI PQRSCSLLST EAGALHVLLP ARGPGPPQRL SFSFGDHLAE
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of human JAK3
- Top Product
- Discover our top product JAK3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- JAK3 (Janus Kinase 3 (JAK3))
- Andere Bezeichnung
- JAK3 (JAK3 Produkte)
- Synonyme
- JAK-3 antikoerper, JAK3_HUMAN antikoerper, JAKL antikoerper, L-JAK antikoerper, LJAK antikoerper, fae antikoerper, wil antikoerper, RATJAK3 antikoerper, JAK antikoerper, Janus kinase 3 antikoerper, JAK3 antikoerper, Jak3 antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Alias Symbols: JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Protein Size: 619 - Molekulargewicht
- 68 kDa
- Gen-ID
- 3718
- NCBI Accession
- NM_000215, NP_000206
- UniProt
- Q8N1E8
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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