SH3KBP1 Antikörper (N-Term)

Produktnummer ABIN2785720

Produktdetails anti-SH3KBP1 Antikörper

Target: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3KBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TGMFPSNFIK ELSGESDELG ISQDEQLSKS SLRETTGSES DGGDSSSTKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SH3KBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SH3KBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 628 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SH3KBP1

Target: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Andere Bezeichnung: SH3KBP1 (SH3KBP1 Produkte)

Synonyme: CD2BP3 antikoerper, CIN85 antikoerper, GIG10 antikoerper, HSB-1 antikoerper, HSB1 antikoerper, MIG18 antikoerper, 1200007H22Rik antikoerper, 1700125L08Rik antikoerper, 5830464D22Rik antikoerper, AI447724 antikoerper, IN85 antikoerper, Ruk antikoerper, Seta antikoerper, SH3 domain containing kinase binding protein 1 antikoerper, SH3-domain kinase binding protein 1 antikoerper, SH3 domain-containing kinase-binding protein 1 antikoerper, SH3KBP1 antikoerper, sh3kbp1 antikoerper, LOC100551401 antikoerper, Sh3kbp1 antikoerper

Hintergrund: This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Alias Symbols: CIN85, GIG10, MIG18, HSB1, HSB-1, CD2BP3
Protein Interaction Partner: PNMA5, ZBTB7B, SH3KBP1, STAP1, FRS3, SPRY2, ASAP2, PSMA3, CBL, UBC, RAF1, LOX, INPP5D, Dlg4, FAP, ARHGAP17, Ap2a1, Irf2bp1, Gcdh, Sept7, Wipf1, Chtf8, Cblb, Shkbp1, Rtkn2, Idh3b, Pik3ap1, Slc25a12, Wasl, Ap2b1, Arap1, Far1, Cltc, Timm50, Actn4, Sept6, Net
Protein Size: 628

Molekulargewicht: 68 kDa

Gen-ID: 30011

NCBI Accession: NM_001024666, NP_001019837

UniProt: Q5JPT5

Pathways: EGFR Signaling Pathway, EGFR Downregulation