UBE4B Antikörper (N-Term)
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- Target Alle UBE4B Antikörper anzeigen
- UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Hund, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UBE4B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SPMFCSVASF GASSLSSLYE SSPAPTPSFW SSVPVMGPSL ASPSRAASQL
- Homologie
- Dog: 79%, Human: 100%, Pig: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against UBE4B. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE4B
- Top Product
- Discover our top product UBE4B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1302 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))
- Andere Bezeichnung
- UBE4B (UBE4B Produkte)
- Synonyme
- ufd2a antikoerper, E4 antikoerper, HDNB1 antikoerper, UBOX3 antikoerper, UFD2 antikoerper, UFD2A antikoerper, 4930551I19Rik antikoerper, 4933406G05Rik antikoerper, AU014668 antikoerper, D4Bwg0973e antikoerper, UFD2a antikoerper, Ufd2p antikoerper, mKIAA0684 antikoerper, ubiquitination factor E4B antikoerper, putative ubiquitin conjugation factor E4 B antikoerper, ubiquitin conjugation factor E4 B antikoerper, ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) antikoerper, Ube4b antikoerper, LINJ_30_1070 antikoerper, LBRM_30_1130 antikoerper, Tsp_12732 antikoerper, Tsp_01624 antikoerper, ube4b antikoerper, UBE4B antikoerper
- Hintergrund
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: E4, HDNB1, KIAA0684, UBOX3, UFD2, UFD2A
Protein Interaction Partner: TRIP12, UBC, FBXW11, HGS, STAM, TP53, MDM2, NUSAP1, NUDCD3, RBM12, PDE3A, CDKN2A, UBL7, UBE2D3, CDC27, TTK, IGBP1, HDLBP, TTC9C, MRPL53, ZFYVE19, SARNP, SRPRB, VPS35, UBA6, VPS29, UFM1, SBDS, VPS36, UBQLN1, UBXN7, UBE2C, AHCYL1, SSSCA1, SF3B4, PPIF, SCO2,
Protein Size: 1302 - Molekulargewicht
- 146 kDa
- Gen-ID
- 10277
- NCBI Accession
- NM_001105562, NP_001099032
- UniProt
- O95155
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