GFRA2 Antikörper (C-Term)

Produktnummer ABIN2785779

Produktdetails anti-GFRA2 Antikörper

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NVSPKGPSFQ ATQAPRVEKT PSLPDDLSDS TSLGTSVITT CTSVQEQGLK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GFRA2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GFRA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 464 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GFRA2

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Andere Bezeichnung: GFRA2 (GFRA2 Produkte)

Synonyme: GDNFRB antikoerper, NRTNR-ALPHA antikoerper, NTNRA antikoerper, RETL2 antikoerper, TRNR2 antikoerper, Retl2 antikoerper, NTNRALPHA antikoerper, ntnra antikoerper, retl2 antikoerper, trnr2 antikoerper, gdnfrb antikoerper, nrtnr-alpha antikoerper, gfra2 antikoerper, GDNF family receptor alpha 2 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 2 antikoerper, GDNF family receptor alpha 2a antikoerper, GFRA2 antikoerper, Gfra2 antikoerper, gfra2 antikoerper, gfra2a antikoerper

Hintergrund: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2
Protein Interaction Partner: PTEN, NRTN, GDNF,
Protein Size: 464

Molekulargewicht: 47 kDa

Gen-ID: 2675

NCBI Accession: NM_001495, NP_001486

UniProt: O00451