KPNA3 Antikörper (N-Term)
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- Target Alle KPNA3 Antikörper anzeigen
- KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KPNA3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- AENPSLENHR IKSFKNKGRD VETMRRHRNE VTVELRKNKR DEHLLKKRNV
- Homologie
- Cow: 77%, Dog: 77%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KPNA3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA3
- Top Product
- Discover our top product KPNA3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 521 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
- Andere Bezeichnung
- KPNA3 (KPNA3 Produkte)
- Synonyme
- IPOA4 antikoerper, si:dz79f24.2 antikoerper, importin antikoerper, SRP1 antikoerper, SRP1gamma antikoerper, SRP4 antikoerper, hSRP1 antikoerper, ipoa4 antikoerper, srp1 antikoerper, srp1gamma antikoerper, srp4 antikoerper, karyopherin (importin) alpha 3 antikoerper, karyopherin alpha 3 (importin alpha 4) antikoerper, karyopherin subunit alpha 3 antikoerper, karyopherin alpha 3 (importin alpha 4) L homeolog antikoerper, Kpna3 antikoerper, kpna3 antikoerper, KPNA3 antikoerper, kpna3.L antikoerper
- Hintergrund
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The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion, larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IPOA4, SRP1gamma, SRP4, hSRP1, SRP1
Protein Interaction Partner: TEX37, SLC5A11, APOL6, RPRD1A, ZCCHC10, MAT2B, NUP50, TSSC4, ZBTB24, DDX21, MTA1, HNRNPC, FTL, MVP, HSF1, UBC, MMS19, KPNA6, MCM6, MCM4, HDAC1, UL122, NACC1, NFE2L2, MYOD1, GTF2H1, GATA6, ERCC3, EPHA2, CBX5, TP53BP1, BARD1, ZNF131, COIL, CUL3, Ranbp2, Mki
Protein Size: 521 - Molekulargewicht
- 58 kDa
- Gen-ID
- 3839
- NCBI Accession
- NM_002267, NP_002258
- UniProt
- O00505
- Pathways
- Protein targeting to Nucleus
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