GBP2 Antikörper (N-Term)

Produktnummer ABIN406421

Produktdetails anti-GBP2 Antikörper

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HTKGIWMWCV PHPKKPEHTL VLLDTEGLGD IEKGDNENDS WIFALAILLS

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GBP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GBP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 591 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Andere Bezeichnung: GBP2 (GBP2 Produkte)

Hintergrund: GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
Alias Symbols: -
Protein Interaction Partner: CNDP2, NANS, RPS6KA1, PEPD, MVD, GSR, GNS, GLA, G6PD, CASP7, CAPN1, ASS1, GSK3B, GADD45A, CSNK2B, BNIP3L, BID, ANXA7, MAPK8IP2, STK3, KLHL20, BTBD2, LSM2, PAFAH1B3, PPP1R8, MAGI1, TFG, SERPINB9, SEPHS1, FXR1, HSPE1, SAT1,
Protein Size: 591

Molekulargewicht: 67 kDa

Gen-ID: 2634

NCBI Accession: NM_004120, NP_004111

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin