Lactate Dehydrogenase A Antikörper (Middle Region)

Produktnummer ABIN2785876

Produktdetails anti-Lactate Dehydrogenase A Antikörper

Target: Lactate Dehydrogenase A (LDHA)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hund, Ziege, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lactate Dehydrogenase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH

Homologie: Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LDHA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 332 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Lactate Dehydrogenase A Antikörper (ABIN2785876)

Listerman, Bledau, Grishina, Neugebauer: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." in: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).

Details zu Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Andere Bezeichnung: LDHA (LDHA Produkte)

Synonyme: GSD11 antikoerper, LDH1 antikoerper, LDHM antikoerper, LDH-M antikoerper, ldh-h antikoerper, ldha antikoerper, ldha-B antikoerper, ldhbb antikoerper, trg-5 antikoerper, Ldh1 antikoerper, Ldhm antikoerper, l7R2 antikoerper, gsd11 antikoerper, ldh-m antikoerper, ldh1 antikoerper, ldhm antikoerper, pig19 antikoerper, ldha1 antikoerper, ldhab antikoerper, LDH-A antikoerper, LDHC antikoerper, lactate dehydrogenase A antikoerper, lactate dehydrogenase B L homeolog antikoerper, lactate dehydrogenase A4 antikoerper, lactate dehydrogenase A L homeolog antikoerper, L-lactate dehydrogenase A chain antikoerper, LDHA antikoerper, ldhb.L antikoerper, Ldha antikoerper, ldha antikoerper, ldha.L antikoerper, LOC100713875 antikoerper

Hintergrund: LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LDH-M, LDH1, PIG19, LDHM, GSD11
Protein Interaction Partner: MAPK10, LDHB, FUS, HUWE1, ISG15, UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, ASB9, RNF2, CNDP2, NAGK, C11orf58, NDRG1, BZW1, KYNU, TCEA1, SORD, SMS, RPS6KA1, PGD, PAFAH1B3, GSR, PDIA3, GNAI3, DLD, CSE1L, LDHAL6B, FTO, BCCIP, XRN1, FBXO6, UPF2, YWHAQ, METT
Protein Size: 332

Molekulargewicht: 37 kDa

Gen-ID: 3939

NCBI Accession: NM_005566, NP_005557

UniProt: P00338

Pathways: Warburg Effekt