14-3-3 sigma/SFN Antikörper (Middle Region)
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- Target Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigen
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- FHYEIANSPE EAISLAKTTF DEAMADLHTL SEDSYKDSTL IMQLLRDNLT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SFN. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SFN
- Top Product
- Discover our top product SFN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 248 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).
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Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).
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- Target
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Andere Bezeichnung
- SFN (SFN Produkte)
- Synonyme
- YWHAS antikoerper, Er antikoerper, Mme1 antikoerper, Ywhas antikoerper, stratifin antikoerper, SFN antikoerper, Sfn antikoerper
- Hintergrund
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SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Alias Symbols: YWHAS
Protein Interaction Partner: FAM9B, RAB3IP, LONRF1, CCDC102B, ZC2HC1C, DTL, FAM53C, MKRN3, FOXO4, MAGEA1, CCNH, SIK3, ZFYVE19, YWHAZ, VCL, UBE2V1, SNRPF, UBE2R2, PAK2, G6PD, TARDBP, EGFR, BAD, MARK3, HDAC7, HDAC5, HDAC4, RAF1, CDC25C, MST1R, ABL1, HNRNPD, ATF2, TRIM32, COPS6, UBC, TP
Protein Size: 248 - Molekulargewicht
- 28 kDa
- Gen-ID
- 2810
- NCBI Accession
- NM_006142, NP_006133
- UniProt
- P31947
- Pathways
- p53 Signalweg, Myometrial Relaxation and Contraction
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