PHGDH Antikörper (Middle Region)

Produktnummer ABIN2785892

Produktdetails anti-PHGDH Antikörper

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CAGAALDVFT EEPPRDRALV DHENVISCPH LGASTKEAQS RCGEEIAVQF

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PHGDH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHGDH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 533 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHGDH

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Andere Bezeichnung: PHGDH (PHGDH Produkte)

Hintergrund: 3-Phosphoglycerate dehydrogenase (PHGDH) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.[supplied by OMIM].
Alias Symbols: 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, ITSN1, ROM1, RPAP3, EPN1, SUMO1, NEDD8, MDM2, SUZ12, RNF2, EZH2, BMI1, FBXO6, TARDBP, EGFR, UBD, CLN5, CLN3, CDK2, PIAS4, FN1, TRAF3IP1, ECT2, MDC1, UQCC3, VASN, TRIM55, SMU1, TRA2A, ADNP, NCSTN, U2AF2, TCERG1, UTP14A, SRSF10, SAP1
Protein Size: 533

Molekulargewicht: 57 kDa

Gen-ID: 26227

NCBI Accession: NM_006623, NP_006614

UniProt: O43175

Pathways: Metabolism of Steroid Hormones and Vitamin D, Warburg Effekt