PHLDA1 Antikörper (C-Term)

Produktnummer ABIN2785898

Produktdetails anti-PHLDA1 Antikörper

Target: PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLDA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LAVKSTRQKQ QHLVQQQPPS QPQPQPQLQP QPQPQPQPQP QPQSQPQPQP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHLDA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHLDA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 401 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PHLDA1 Antikörper (ABIN2785898)

Tsuda, Davis, Argani, Shukla, McGill, Nagai, Saito, Laé, Fisher, Ladanyi: "TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition." in: Cancer research, Vol. 67, Issue 3, pp. 919-29, (2007) (PubMed).

Details zu PHLDA1

Target: PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))

Andere Bezeichnung: PHLDA1 (PHLDA1 Produkte)

Synonyme: DT1P1B11 antikoerper, PHRIP antikoerper, TDAG51 antikoerper, Tdag antikoerper, pleckstrin homology like domain family A member 1 antikoerper, pleckstrin homology like domain, family A, member 1 antikoerper, pleckstrin homology-like domain, family A, member 1 antikoerper, pleckstrin homology-like domain, family A, member 1 L homeolog antikoerper, PHLDA1 antikoerper, Phlda1 antikoerper, phlda1.L antikoerper

Hintergrund: PHLDA1 is an evolutionarily conserved proline-histidine rich nuclear protein. It may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.
Alias Symbols: DT1P1B11, MGC131738, PHRIP, TDAG51
Protein Interaction Partner: UBC, SUMO1, MDFI, EGFR, APP, DNAJB1, HSPB1, HSPA4, ELAVL1, KRTAP4-12, RPL14, PLSCR1, HSPA4L, EIF3D, PABPC4,
Protein Size: 401

Molekulargewicht: 45 kDa

Gen-ID: 22822

NCBI Accession: NM_007350, NP_031376

UniProt: Q8WV24