Peroxiredoxin 5 Antikörper (Middle Region)

Produktnummer ABIN2785911

Produktdetails anti-Peroxiredoxin 5 Antikörper

Target: Peroxiredoxin 5 (PRDX5)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Ziege, Hund, Meerschweinchen, Pferd, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TDLLLDDSLV SIFGNRRLKR FSMVVQDGIV KALNVEPDGT GLTCSLAPNI

Homologie: Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDX5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRDX5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 125 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Peroxiredoxin 5 Antikörper (ABIN2785911)

Trujillo, Clippe, Manta, Ferrer-Sueta, Smeets, Declercq, Knoops, Radi: "Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation." in: Archives of biochemistry and biophysics, Vol. 467, Issue 1, pp. 95-106, (2007) (PubMed).

Details zu Peroxiredoxin 5

Target: Peroxiredoxin 5 (PRDX5)

Andere Bezeichnung: PRDX5 (PRDX5 Produkte)

Synonyme: acr1 antikoerper, aoeb166 antikoerper, pmp20 antikoerper, prx-5 antikoerper, prx5 antikoerper, prxv antikoerper, sbbi10 antikoerper, GB16965 antikoerper, zgc:112318 antikoerper, PRDX5 antikoerper, CG 32920 antikoerper, CG 7217 antikoerper, CG32920 antikoerper, CG7217 antikoerper, Dmel\\CG7217 antikoerper, dPrx5 antikoerper, dprx5 antikoerper, ACR1 antikoerper, AOEB166 antikoerper, B166 antikoerper, PLP antikoerper, PMP20 antikoerper, PRDX6 antikoerper, PRXV antikoerper, prx-V antikoerper, AOPP antikoerper, Pmp20 antikoerper, Prdx6 antikoerper, PrxV antikoerper, Aoeb166 antikoerper, Prx V antikoerper, peroxiredoxin 5 L homeolog antikoerper, peroxiredoxin-5, mitochondrial antikoerper, peroxiredoxin 5 antikoerper, Peroxiredoxin 5 antikoerper, prdx5.L antikoerper, LOC552429 antikoerper, prdx5 antikoerper, PRDX5 antikoerper, Prx5 antikoerper, Prdx5 antikoerper

Hintergrund: PRDX5 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10
Protein Interaction Partner: UBC, MDM2, WWOX, ATF2, PEX5, TOMM40, PRDX6, STAM, SUMO1, UBE2B, UBE2A, PRDX2, VAMP2, SOD1, RPS12, RAD23B, PTMS, PRDX1, MDH1, IGBP1, APP, ZFYVE19, PSRC1, GINS4, UBAP2, PTPN23, PTGR1, PARK7, IFT27, SEC24A, SSSCA1, ICT1, BABAM1, CCDC90B,
Protein Size: 125

Molekulargewicht: 14 kDa

Gen-ID: 25824

NCBI Accession: NM_181652, NP_857635

UniProt: B7ZVW3

Pathways: Cell RedoxHomeostasis