ANGPTL2 Antikörper (N-Term)

Produktnummer ABIN2785913

Produktdetails anti-ANGPTL2 Antikörper

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NSKEPEVLLE NRVHKQELEL LNNELLKQKR QIETLQQLVE VDGGIVSEVK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ANGPTL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANGPTL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 493 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ANGPTL2 Antikörper (ABIN2785913)

Doblinger, Höcherl, Mederle, Kattler, Walter, Hansen, Jensen, Castrop: "Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II." in: American journal of physiology. Renal physiology, Vol. 302, Issue 10, pp. F1313-24, (2012) (PubMed).

Sun, Zheng, Chen, Zeng, Liu, Li: "Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy." in: Nephron. Experimental nephrology, Vol. 105, Issue 4, pp. e117-23, (2007) (PubMed).

Details zu ANGPTL2

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Andere Bezeichnung: ANGPTL2 (ANGPTL2 Produkte)

Hintergrund: Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-127 AL598400.1 2-128 128-451 AL598400.1 129-452 452-2289 BC012368.1 325-2162 2290-3572 AK074726.1 1294-2576
Alias Symbols: ARP2, HARP, MGC8889
Protein Size: 493

Molekulargewicht: 57 kDa

Gen-ID: 23452

NCBI Accession: NM_012098, NP_036230

UniProt: Q9UKU9