CDC42EP4 Antikörper (N-Term)

Produktnummer ABIN2785914

Produktdetails anti-CDC42EP4 Antikörper

Target: CDC42EP4 (CDC42 Effector Protein (Rho GTPase Binding) 4 (CDC42EP4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42EP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSSKRSLLSR KFRGSKRSQS VTRGEREQRD MLGSLRDSAL FVKNAMSLPQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC42EP4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDC42EP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 356 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC42EP4

Target: CDC42EP4 (CDC42 Effector Protein (Rho GTPase Binding) 4 (CDC42EP4))

Andere Bezeichnung: CDC42EP4 (CDC42EP4 Produkte)

Hintergrund: CDC42EP4 is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. The protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, the protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
Alias Symbols: BORG4, CEP4, KAIA1777, MGC17125, MGC3740
Protein Interaction Partner: FAM9B, SRPK2, UBC, VCP, APP, LNX1, ELAVL1, CDC42, POLR3H, WDR6, RHOQ, TGFBR1,
Protein Size: 356

Molekulargewicht: 38 kDa

Gen-ID: 23580

NCBI Accession: NM_012121, NP_036253

UniProt: Q9H3Q1