SESN1 Antikörper (Middle Region)
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- Target Alle SESN1 Antikörper anzeigen
- SESN1 (Sestrin 1 (SESN1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SESN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KWLNGLENAP QKLQNLGELN KVLAHRPWLI TKEHIEGLLK AEEHSWSLAE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SESN1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human SESN1
- Top Product
- Discover our top product SESN1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SESN1 (Sestrin 1 (SESN1))
- Andere Bezeichnung
- SESN1 (SESN1 Produkte)
- Synonyme
- zgc:91970 antikoerper, sestrin-1 antikoerper, SESN1 antikoerper, XPA26 antikoerper, pa26 antikoerper, sest1 antikoerper, PA26 antikoerper, SEST1 antikoerper, 1110002G11Rik antikoerper, AU044290 antikoerper, Pa26 antikoerper, Sest1 antikoerper, sesn1-A antikoerper, sestrin 1 antikoerper, sestrin 1 L homeolog antikoerper, SESN1 antikoerper, sesn1 antikoerper, Sesn1 antikoerper, sesn1.L antikoerper
- Hintergrund
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This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: PA26, SEST1
Protein Interaction Partner: UBC, RBX1, KEAP1, SQSTM1, PRDX1,
Protein Size: 551 - Molekulargewicht
- 64 kDa
- Gen-ID
- 27244
- NCBI Accession
- NM_014454, NP_055269
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