TMOD3 Antikörper (Middle Region)

Produktnummer ABIN2786043

Produktdetails anti-TMOD3 Antikörper

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMOD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ITNTKFCNIM GSSNGVDQEH FSNVVKGEKI LPVFDEPPNP TNVEESLKRT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TMOD3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMOD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 352 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TMOD3

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Andere Bezeichnung: TMOD3 (TMOD3 Produkte)

Synonyme: TMOD3 antikoerper, tropomodulin-3 antikoerper, UTMOD antikoerper, MGC53545 antikoerper, U-Tmod antikoerper, tropomodulin 3 antikoerper, tropomodulin 3 S homeolog antikoerper, TMOD3 antikoerper, Tmod3 antikoerper, tmod3.S antikoerper, tmod3 antikoerper

Hintergrund: TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
Alias Symbols: UTMOD
Protein Interaction Partner: UBC, PABPC1, YWHAE, PSMD9, PPP1CA, DHX15, PAN2, CSNK2A1, HNRNPUL2, PPIL3, AHCYL1, SULT1A1, PSMC4, PSMB7, NPC1, ATP6V1B1, LRRK2, FBXO25, ISG15, ARRB2, ARRB1, ELAVL1, SUMO2, DUSP23, TNFSF11, MAP1LC3B, Poc1b, Tubgcp3, Sass6, Trim69, Stag2, Pafah1b1, Erh, Cdk
Protein Size: 352

Molekulargewicht: 39 kDa

Gen-ID: 29766

NCBI Accession: NM_014547, NP_055362

UniProt: Q9NYL9

Pathways: Regulation of Actin Filament Polymerization