FAM120A Antikörper (Middle Region)

Produktnummer ABIN2786049

Produktdetails anti-FAM120A Antikörper

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM120A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SGGATNHISG NKIGWEKTGS HSEPQARGDP GDQTKAEGSS TASSGSQLAE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FAM120A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM120A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1118 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FAM120A

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Andere Bezeichnung: FAM120A (FAM120A Produkte)

Synonyme: MGC89333 antikoerper, fam120a antikoerper, C9orf10 antikoerper, Ossa antikoerper, DNAPTP1 antikoerper, DNAPTP5 antikoerper, OSSA antikoerper, RGD1306643 antikoerper, family with sequence similarity 120A antikoerper, family with sequence similarity 120, member A antikoerper, fam120a antikoerper, Fam120a antikoerper, FAM120A antikoerper

Hintergrund: FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Interaction Partner: SPRTN, CEP250, SUMO2, STAU1, UBC, PASK, SUMO1, NEDD8, RNF2, EZH2, BMI1, HECW2, TARDBP, CFTR, GRK5, CAND1, CUL3, SIRT7, Ybx1,
Protein Size: 1118

Molekulargewicht: 122 kDa

Gen-ID: 23196

NCBI Accession: NM_014612, NP_055427

UniProt: Q9NZB2