SAPS1 Antikörper (N-Term)

Produktnummer ABIN2786061

Produktdetails anti-SAPS1 Antikörper

Target: SAPS1 (SAPS Domain Family, Member 1 (SAPS1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MFWKFDLHTS SHLDTLLERE DLSLPELLDE EDVLQECKVV NRKLLDFLLQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SAPS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 881 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SAPS1

Target: SAPS1 (SAPS Domain Family, Member 1 (SAPS1))

Andere Bezeichnung: PPP6R1 (SAPS1 Produkte)

Synonyme: KIAA1115 antikoerper, PP6R1 antikoerper, SAP190 antikoerper, SAPS1 antikoerper, 2010309P17Rik antikoerper, AI836219 antikoerper, B430201G11Rik antikoerper, D030074N20Rik antikoerper, Pp6r1 antikoerper, Saps1 antikoerper, mKIAA1115 antikoerper, RGD1311409 antikoerper, pp6r1 antikoerper, MGC69001 antikoerper, protein phosphatase 6 regulatory subunit 1 antikoerper, protein phosphatase 6, regulatory subunit 1 antikoerper, protein phosphatase 6 regulatory subunit 1 L homeolog antikoerper, PPP6R1 antikoerper, Ppp6r1 antikoerper, ppp6r1.L antikoerper

Hintergrund: Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C, MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]).
Alias Symbols: KIAA1115, MGC138185, MGC142003, PP6R1, SAP190, SAPS1
Protein Interaction Partner: UBC, AGO1, ANKRD52, MOB1B, ANKRD44, ACAD11, SRPRB, PPP6R3, MOB1A, CNOT10, ANKRD28, CNOT1, ILVBL, PFDN6, C2CD5, KNTC1, PPP6R2, GTF3C4, ARHGEF2, USP10, SGPL1, IKBKAP, TTF2, SRPR, PPP6C, PFDN5, PFDN2, PDCD2, HSPA4, HADHB, HADHA, ACSL3, ALDH3A2, EGFR, HDAC11,
Protein Size: 881

Molekulargewicht: 97 kDa

Gen-ID: 22870

NCBI Accession: NM_014931, NP_055746

UniProt: Q9UPN7