SMG5 Antikörper (N-Term)

Produktnummer ABIN2786101

Produktdetails anti-SMG5 Antikörper

Target: SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MSQGPPTGES SEPEAKVLHT KRLYRAVVEA VHRLDLILCN KTAYQEVFKP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SMG5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMG5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1016 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMG5

Target: SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))

Andere Bezeichnung: SMG5 (SMG5 Produkte)

Synonyme: BC024683 antikoerper, mKIAA1089 antikoerper, EST1B antikoerper, LPTS-RP1 antikoerper, LPTSRP1 antikoerper, SMG-5 antikoerper, SMG5, nonsense mediated mRNA decay factor antikoerper, Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) antikoerper, SMG5 nonsense mediated mRNA decay factor antikoerper, SMG5 antikoerper, Smg5 antikoerper

Hintergrund: SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].
Alias Symbols: EST1B, FLJ34864, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5
Protein Interaction Partner: RBM8A, UPF1, PHB, ZWINT, UBC, APP, HDAC8, STUB1, SMG7, SMG6, SMG1, TERT,
Protein Size: 1016

Molekulargewicht: 114 kDa

Gen-ID: 23381

NCBI Accession: NM_015327, NP_056142

UniProt: Q9UPR3