COG4 Antikörper (Middle Region)

Produktnummer ABIN2786106

Produktdetails anti-COG4 Antikörper

Target: COG4 (Component of Oligomeric Golgi Complex 4 (COG4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TSLVAVELEK VVLKSTFNRL GGLQFDKELR SLIAYLTTVT TWTIRDKFAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against COG4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COG4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 789 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-COG4 Antikörper (ABIN2786106)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Details zu COG4

Target: COG4 (Component of Oligomeric Golgi Complex 4 (COG4))

Andere Bezeichnung: COG4 (COG4 Produkte)

Synonyme: COG4 antikoerper, DKFZp470I1314 antikoerper, CDG2J antikoerper, COD1 antikoerper, AW554810 antikoerper, D8Ertd515e antikoerper, zgc:136860 antikoerper, component of oligomeric golgi complex 4 antikoerper, COG4 antikoerper, cog4 antikoerper, Cog4 antikoerper

Hintergrund: Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4.Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-265 AK096557.1 1-265 266-555 BP282697.1 230-519 556-1072 AU125729.1 34-550 1073-2838 AL050101.1 375-2140
Alias Symbols: COD1, DKFZp586E1519, CDG2J
Protein Interaction Partner: UBC, EGFR, COG6, VCP, COG7, COG8, COG3, COG5, COG1, RPS20, CUL4B, SEPT2, APC, COG2,
Protein Size: 789

Molekulargewicht: 89 kDa

Gen-ID: 25839

NCBI Accession: NM_015386, NP_056201

UniProt: Q9H9E3