SENP3 Antikörper (N-Term)

Produktnummer ABIN2786148

Produktdetails anti-SENP3 Antikörper

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SENP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: PPPKPRLKSG GGFGPDPGSG TTVPARRLPV PRPSFDASAS EEEEEEEEEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SENP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SENP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 574 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SENP3

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Andere Bezeichnung: SENP3 (SENP3 Produkte)

Hintergrund: SENP3 is a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.
Alias Symbols: DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3
Protein Interaction Partner: HIF1A, EP300, UBC, SUMO2, WDR5, ASH2L, KMT2D, RBBP5, KMT2A, MEN1, RNF2, HECW2, SOX2, LAS1L, PELP1, CDK6, CDK4, MOV10, CHCHD4, DHX15, ILF3, TRIM63, TRIM54, USP21, USP15, CDKN2A, RPS18, RPS11, RPS8, RPS4X, RPLP0, NPM1, PIDD1, NR1H2, TP53, MDM2, STUB1, HSP90
Protein Size: 574

Molekulargewicht: 65 kDa

Gen-ID: 26168

NCBI Accession: NM_015670, NP_056485

UniProt: Q9H4L4