COPG Antikörper (N-Term)

Produktnummer ABIN2786156

Produktdetails anti-COPG Antikörper

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLKKFDKKDE ESGGGSNPFQ HLEKSAVLQE ARVFNETPIN PRKCAHILTK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against COPG. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COPG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 874 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COPG

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Andere Bezeichnung: COPG (COPG Produkte)

Hintergrund: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPG1, FLJ21068, COPG
Protein Interaction Partner: HUWE1, UBC, SUMO2, NUDCD1, RNF2, RABGAP1, COPZ1, COPE, TELO2, TTI1, ARHGEF10, COPB2, TLE3, TCP1, RUFY1, DDB2, COPB1, ARCN1, UBD, NPM1, PPBP, FN1, COPG2, COPA, COPZ2, COPG1, SACM1L, TMED10, SIRT7, H2AFX, MYC, ATG101, PMS2, KEAP1, GBF1, TAPBP, PTGES3, RHOQ,
Protein Size: 874

Molekulargewicht: 98 kDa

Gen-ID: 22820

NCBI Accession: NM_016128, NP_057212

UniProt: Q9Y678