K-RAS Antikörper (N-Term)

Produktnummer ABIN2786191

Produktdetails anti-K-RAS Antikörper

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser K-RAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TEYKLVVVGA GGVGKSALTI QLIQNHFVDE YDPTIEDSYR KQVVIDGETC

Spezifität: 100 % homologous to human KRAS, NRAS and HRAS.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KRAS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KRAS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 189 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung: KRAS (KRAS Produkte)

Substanzklasse: Viral Protein

Hintergrund: KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Alias Symbols: C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Protein Interaction Partner: RBPMS, UBC, PSMA3, ARAF, MDFI, TRAF6, BCL2, BTRC, RAF1, MAPK1, PHB, DDX50, EGLN1, DDX47, RALGDS, RGL2, PIK3R2, LPAR1, ADH6, APP, ELAVL1, CALM1, IGSF21, CCT7, PDE4DIP, DNAJA3, EEF1A1, RASGRF2, RASSF2, RAP1GDS1, RASGRP2, RASSF5, SHOC2, PGGT1B, PIK3CG, EPB42
Protein Size: 189

Molekulargewicht: 22 kDa

Gen-ID: 3845

NCBI Accession: NM_033360, NP_203524

UniProt: P01111