K-RAS Antikörper (N-Term)

Produktnummer ABIN2786191

Produktdetails anti-K-RAS Antikörper

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser K-RAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TEYKLVVVGA GGVGKSALTI QLIQNHFVDE YDPTIEDSYR KQVVIDGETC

Spezifität: 100 % homologous to human KRAS, NRAS and HRAS.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KRAS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KRAS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 189 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung: KRAS (KRAS Produkte)

Synonyme: wu:fa04e08 antikoerper, wu:fc14b12 antikoerper, wu:fc23g10 antikoerper, wu:fj89d12 antikoerper, zgc:85725 antikoerper, Kras2 antikoerper, c-Ki-ras antikoerper, p21 antikoerper, C-K-RAS antikoerper, CFC2 antikoerper, K-RAS2A antikoerper, K-RAS2B antikoerper, K-RAS4A antikoerper, K-RAS4B antikoerper, KI-RAS antikoerper, KRAS1 antikoerper, KRAS2 antikoerper, NS antikoerper, NS3 antikoerper, RASK2 antikoerper, AI929937 antikoerper, K-ras antikoerper, Ki-ras antikoerper, Kras-2 antikoerper, p21B antikoerper, ras antikoerper, k-ras antikoerper, kras antikoerper, kras-a antikoerper, kras-b antikoerper, rask2 antikoerper, K-RAS antikoerper, p21ras antikoerper, KRAS proto-oncogene, GTPase antikoerper, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog antikoerper, Kirsten rat sarcoma viral oncogene homolog antikoerper, semicolonial-7 antikoerper, Ras family protein antikoerper, GTPase KRas antikoerper, Kirsten rat sarcoma viral oncogene homolog S homeolog antikoerper, KRAS antikoerper, kras antikoerper, Kras antikoerper, smco-7 antikoerper, PGTG_03066 antikoerper, Tsp_02666 antikoerper, Tsp_01642 antikoerper, rask antikoerper, kras.S antikoerper

Substanzklasse: Viral Protein

Hintergrund: KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Alias Symbols: C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Protein Interaction Partner: RBPMS, UBC, PSMA3, ARAF, MDFI, TRAF6, BCL2, BTRC, RAF1, MAPK1, PHB, DDX50, EGLN1, DDX47, RALGDS, RGL2, PIK3R2, LPAR1, ADH6, APP, ELAVL1, CALM1, IGSF21, CCT7, PDE4DIP, DNAJA3, EEF1A1, RASGRF2, RASSF2, RAP1GDS1, RASGRP2, RASSF5, SHOC2, PGGT1B, PIK3CG, EPB42
Protein Size: 189

Molekulargewicht: 22 kDa

Gen-ID: 3845

NCBI Accession: NM_033360, NP_203524

UniProt: P01111