COX18 Antikörper (Middle Region)

Produktnummer ABIN2786331

Produktdetails anti-COX18 Antikörper

Target: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LCSSFVGLSQ NLLLRSPGFR QLCRIPSTKS DSETPYKDIF AAFNTKFISR

Homologie: Cow: 79%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against COX18. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COX18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 333 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COX18

Target: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Andere Bezeichnung: COX18 (COX18 Produkte)

Synonyme: COX18HS antikoerper, BC038311 antikoerper, RGD1559547 antikoerper, COX18 cytochrome c oxidase assembly factor L homeolog antikoerper, COX18, cytochrome c oxidase assembly factor antikoerper, cytochrome c oxidase assembly protein 18 antikoerper, cox18.L antikoerper, COX18 antikoerper, Cox18 antikoerper

Hintergrund: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c
Alias Symbols: COX18HS, FLJ38991, MGC126733
Protein Size: 333

Molekulargewicht: 37 kDa

Gen-ID: 285521

NCBI Accession: NM_173827, NP_776188

UniProt: Q8N8Q8