NUP43 Antikörper (Middle Region)

Produktnummer ABIN2786439

Produktdetails anti-NUP43 Antikörper

Target: NUP43 (Nucleoporin 43kDa (NUP43))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HQSVISSWLS TDPAKDRIEI TSLLPSRSLS VNTLDVLGPC LVCGTDAEAI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NUP43. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NUP43

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 380 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NUP43 Antikörper (ABIN2786439)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu NUP43

Target: NUP43 (Nucleoporin 43kDa (NUP43))

Andere Bezeichnung: NUP43 (NUP43 Produkte)

Synonyme: MGC184722 antikoerper, MGC154553 antikoerper, 2610016K01Rik antikoerper, 2610529I12Rik antikoerper, AA409950 antikoerper, p42 antikoerper, bA350J20.1 antikoerper, nucleoporin 43 antikoerper, nucleoporin 43kDa antikoerper, nucleoporin Nup43 antikoerper, nucleoporin 43kDa S homeolog antikoerper, NUP43 antikoerper, nup43 antikoerper, LOC696374 antikoerper, nup43.S antikoerper, Nup43 antikoerper

Hintergrund: NUP43 is the component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 BG567254.1 2-11 11-24 CB989591.1 28-41 25-47 AK074311.1 1-23 48-1751 AF514997.1 1-1704 1752-2581 BC047539.1 2681-3510 2582-2745 BC046637.1 2350-2513 2746-2818 BG527619.1 33-105 c 2819-3862 BC046637.1 2587-3630
Alias Symbols: FLJ13287, bA350J20.1, p42
Protein Interaction Partner: UBC, SUMO1, SEH1L, DCTN2, TP53RK, RAB3GAP2, NUP107, UBD, ISG15, CUL4A, DDB1, Nup98, NUP37, NUP85, NUP133, NUP160,
Protein Size: 380

Molekulargewicht: 42 kDa

Gen-ID: 348995

NCBI Accession: NM_198887, NP_942590

UniProt: Q8NFH3