PPOX Antikörper (N-Term)

Produktnummer ABIN2786509

Produktdetails anti-PPOX Antikörper

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSERLGGWIR SVRGPNGAIF ELGPRGIRPA GALGARTLLL VSELGLDSEV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PPOX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPOX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 477 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PPOX Antikörper (ABIN2786509)

de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." in: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

Details zu PPOX

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Andere Bezeichnung: PPOX (PPOX Produkte)

Synonyme: PPO antikoerper, V290M antikoerper, VP antikoerper, Ppo antikoerper, BcDNA:LD41392 antikoerper, CG5796 antikoerper, Dmel\\CG5796 antikoerper, ESTS:9F2T antikoerper, zgc:123252 antikoerper, HEMG1 antikoerper, PPO1 antikoerper, PROTOPORPHYRINOGEN OXIDASE antikoerper, TC0121 antikoerper, hemG antikoerper, protoporphyrinogen oxidase antikoerper, Protoporphyrinogen oxidase antikoerper, Flavin containing amine oxidoreductase family antikoerper, polyphenol oxidase, chloroplastic antikoerper, PPOX antikoerper, Ppox antikoerper, ppox antikoerper, hemY antikoerper, TC_RS00645 antikoerper, Mrub_1406 antikoerper, Mesil_2992 antikoerper, Trad_0583 antikoerper, Calni_0746 antikoerper, Ocepr_1049 antikoerper, Tmar_0766 antikoerper, Intca_1907 antikoerper, Despr_0642 antikoerper, Plabr_2407 antikoerper, Deipr_2130 antikoerper, Hipma_0622 antikoerper, LOC110782963 antikoerper

Hintergrund: PPOX catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX..This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: MGC8485, PPO, V290M, VP
Protein Interaction Partner: HNRNPD, UBC, COPS5, HAP1, PPOX, IMMT,
Protein Size: 477

Molekulargewicht: 51 kDa

Gen-ID: 5498

NCBI Accession: NM_000309, NP_000300

UniProt: P50336

Pathways: Synaptic Membrane, Feeding Behaviour