BLMH Antikörper (Middle Region)
-
- Target Alle BLMH Antikörper anzeigen
- BLMH (Bleomycin Hydrolase (BLMH))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human, Ratte, Maus, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Rind (Kuh), Pferd, Kaninchen
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser BLMH Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- EYLSNMVGGR KTLYNNQPID FLKKMVAASI KDGEAVWFGC DVGKHFNSKL
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against BLMH. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human BLMH
- Top Product
- Discover our top product BLMH Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 455 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- BLMH (Bleomycin Hydrolase (BLMH))
- Andere Bezeichnung
- BLMH (BLMH Produkte)
- Synonyme
- AI035728 antikoerper, Bh antikoerper, Bmh antikoerper, wu:fb13c01 antikoerper, zgc:66261 antikoerper, bh antikoerper, bmh antikoerper, BH antikoerper, BMH antikoerper, bleomycin hydrolase antikoerper, Bleomycin hydrolase antikoerper, bleomycin hydrolase S homeolog antikoerper, BLMH antikoerper, pepC antikoerper, LOC5569945 antikoerper, Apre_0140 antikoerper, Apar_0899 antikoerper, Smon_1289 antikoerper, Kfla_1242 antikoerper, Snas_3912 antikoerper, BLJ_1941 antikoerper, Olsu_1085 antikoerper, PGTDC60_0106 antikoerper, Blmh antikoerper, blmh antikoerper, blmh.S antikoerper
- Hintergrund
-
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BH, BMH
Protein Interaction Partner: NUDT12, WDYHV1, BLMH, UBC, ZBTB1, SH3GLB2, LZTFL1, GORASP2, PES1, GTF2A1, AP1M2, CYP2C8, RNF32, ECSIT, MAST1, COPS5, CUL4B, SUMO2, PDPK1, Fam134a, USP53, KBTBD7, RPL11, UBE2I, TRIO, RPL29, APP,
Protein Size: 455 - Molekulargewicht
- 52 kDa
- Gen-ID
- 642
- NCBI Accession
- NM_000386, NP_000377
- UniProt
- Q13867
-