ACO2 Antikörper (N-Term)

Produktnummer ABIN2786627

Produktdetails anti-ACO2 Antikörper

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Saccharomyces cerevisiae, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LQFISSGLSK VAVPSTIHCD HLIEAQVGGE KDLRRAKDIN QEVYNFLATA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ACO2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACO2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 780 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACO2 Antikörper (ABIN2786627)

Schauer, Freund, Prenni, Curthoys: "Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 305, Issue 5, pp. F628-40, (2013) (PubMed).

Freund, Prenni, Curthoys: "Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 304, Issue 2, pp. F145-55, (2013) (PubMed).

Details zu ACO2

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Andere Bezeichnung: ACO2 (ACO2 Produkte)

Synonyme: DDBDRAFT_0206187 antikoerper, DDBDRAFT_0230168 antikoerper, DDB_0206187 antikoerper, DDB_0230168 antikoerper, aconitase 2 antikoerper, F10M23.310 antikoerper, F10M23_310 antikoerper, ACONM antikoerper, ICRD antikoerper, Aco-2 antikoerper, Aco3 antikoerper, D10Wsu183e antikoerper, cb1017 antikoerper, wu:fa10e03 antikoerper, wu:fb69g04 antikoerper, wu:fc20c11 antikoerper, aconitase 2 antikoerper, aconitase 2 S homeolog antikoerper, aconitate hydratase, mitochondrial antikoerper, aconitase, mitochondrial antikoerper, mitochondrial aconitate hydratase antikoerper, aconitase 2, mitochondrial antikoerper, Probable aconitate hydratase, mitochondrial antikoerper, ACO2 antikoerper, aco2.S antikoerper, Bm1_07420 antikoerper, aco2 antikoerper, ach1 antikoerper, Aco2 antikoerper, aco-2 antikoerper

Hintergrund: ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACONM, MGC20605, MGC33908
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, MDM2, ASB9, VCAM1, ITGA4, AK3, SIN3A, ACAA2, APP, ACAT1, ATXN1L, SUMO4, PSMD4, SRRM2,
Protein Size: 780

Molekulargewicht: 82 kDa

Gen-ID: 50

NCBI Accession: NM_001098, NP_001089

UniProt: Q99798