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RASGRF1 Antikörper (Middle Region)

RASGRF1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2786746
  • Target Alle RASGRF1 Antikörper anzeigen
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    Bindungsspezifität
    • 15
    • 12
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 26
    • 25
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 50
    Kaninchen
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RASGRF1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 22
    • 15
    • 13
    • 13
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    PMSEKGKITR GRLGSLSLKK EGERQCFLFS KHLIICTRGS GGKLHLTKNG
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RASGRF1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RASGRF1
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1273 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    Andere Bezeichnung
    RASGRF1 (RASGRF1 Produkte)
    Synonyme
    CDC25 antikoerper, CDC25L antikoerper, GNRP antikoerper, GRF1 antikoerper, GRF55 antikoerper, H-GRF55 antikoerper, PP13187 antikoerper, ras-GRF1 antikoerper, AI844718 antikoerper, CDC25Mm antikoerper, Grf1 antikoerper, Grfbeta antikoerper, P190-A antikoerper, Ras-GRF1 antikoerper, p190 antikoerper, p190RhoGEF antikoerper, cdc25 antikoerper, rasgrf1 antikoerper, Ras protein specific guanine nucleotide releasing factor 1 antikoerper, RAS protein-specific guanine nucleotide-releasing factor 1 antikoerper, Ras protein specific guanine nucleotide releasing factor 1 S homeolog antikoerper, si:ch211-234p18.3 antikoerper, RASGRF1 antikoerper, Rasgrf1 antikoerper, rasgrf1.S antikoerper, si:ch211-234p18.3 antikoerper, rasgrf1 antikoerper
    Hintergrund
    The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
    Protein Interaction Partner: EHD4, SNRNP70, CEBPA, ADRBK1, MYC, UBC, TNK2, YWHAE, USP8, RAC1, PRKACA, NTRK2, RRAS2, NTRK3, NTRK1, RHOA, YWHAB, PPP1R9B, MARK3, HRAS,
    Protein Size: 1273
    Molekulargewicht
    145 kDa
    Gen-ID
    5923
    NCBI Accession
    NM_002891, NP_002882
    UniProt
    Q13972
    Pathways
    RTK Signalweg, Zellzyklus, M Phase
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