RASGRF1 Antikörper (N-Term)

Produktnummer ABIN2786747

Produktdetails anti-RASGRF1 Antikörper

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RELDNNRSAL SAASAFAIAT AGANEGTPNK EKYRRMSLAS AGFPPDQRNG

Spezifität: Predicted to recognized both human RASGRF1 isoforms (145, 55kD)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RASGRF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RASGRF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 489 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Andere Bezeichnung: RASGRF1 (RASGRF1 Produkte)

Synonyme: CDC25 antikoerper, CDC25L antikoerper, GNRP antikoerper, GRF1 antikoerper, GRF55 antikoerper, H-GRF55 antikoerper, PP13187 antikoerper, ras-GRF1 antikoerper, AI844718 antikoerper, CDC25Mm antikoerper, Grf1 antikoerper, Grfbeta antikoerper, P190-A antikoerper, Ras-GRF1 antikoerper, p190 antikoerper, p190RhoGEF antikoerper, cdc25 antikoerper, rasgrf1 antikoerper, Ras protein specific guanine nucleotide releasing factor 1 antikoerper, RAS protein-specific guanine nucleotide-releasing factor 1 antikoerper, Ras protein specific guanine nucleotide releasing factor 1 S homeolog antikoerper, si:ch211-234p18.3 antikoerper, RASGRF1 antikoerper, Rasgrf1 antikoerper, rasgrf1.S antikoerper, si:ch211-234p18.3 antikoerper, rasgrf1 antikoerper

Hintergrund: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein.
Alias Symbols: CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
Protein Interaction Partner: EHD4, SNRNP70, CEBPA, ADRBK1, MYC, UBC, TNK2, YWHAE, USP8, RAC1, PRKACA, NTRK2, RRAS2, NTRK3, NTRK1, RHOA, YWHAB, PPP1R9B, MARK3, HRAS,
Protein Size: 489

Molekulargewicht: 54 kDa

Gen-ID: 5923

NCBI Accession: NM_153815, NP_722522

Pathways: RTK Signalweg, Zellzyklus, M Phase