TBC1D7 Antikörper (C-Term)
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- Target Alle TBC1D7 Antikörper anzeigen
- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBC1D7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ISRCFVKQLN NKYRDALPQL PKAFEQYLNL EDSRLLSHLK TCSAVSKLPY
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Tbc1d7. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Tbc1d7
- Top Product
- Discover our top product TBC1D7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 293 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
- Andere Bezeichnung
- Tbc1d7 (TBC1D7 Produkte)
- Synonyme
- PIG51 antikoerper, TBC7 antikoerper, dJ257A7.3 antikoerper, 2610009C09Rik antikoerper, TBC1 domain family member 7 antikoerper, TBC1 domain family, member 7 antikoerper, TBC1D7 antikoerper, Tbc1d7 antikoerper
- Hintergrund
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Tbc1d7 is a component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Alias Symbols: 2610009C09Rik
Protein Interaction Partner: Ywhae,
Protein Size: 293 - Molekulargewicht
- 32 kDa
- Gen-ID
- 67046
- NCBI Accession
- NM_025935, NP_080211
- UniProt
- Q9D0K0
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