PINX1 Antikörper (Middle Region)

Produktnummer ABIN2787041

Produktdetails anti-PINX1 Antikörper

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PINX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PINX1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PINX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 328 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PINX1

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Andere Bezeichnung: PINX1 (PINX1 Produkte)

Synonyme: PINX1 antikoerper, LPTL antikoerper, LPTS antikoerper, 2210403I16Rik antikoerper, 2610028A01Rik antikoerper, 67-11-3 antikoerper, AU024023 antikoerper, LPTS1 antikoerper, RGD1566025 antikoerper, PIN2/TERF1 interacting telomerase inhibitor 1 antikoerper, PIN2/TERF1 interacting, telomerase inhibitor 1 antikoerper, PINX1 antikoerper, Pinx1 antikoerper

Hintergrund: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Alias Symbols: FLJ20565, LPTL, LPTS, MGC8850
Protein Interaction Partner: UBC, CACYBP, TP63, GABPA, TERF1, DHX15, AIDA, MCRS1, PAFAH1B2, TERT, MPZ, HRNR, PLEKHJ1, PABPC1, GTPBP4, PABPC4, TXN, RPS28, RPS19, RPS16, RPS10, RPS3A, RPL31, RPL23A, CAPRIN1, CALM3, AHCY,
Protein Size: 328

Molekulargewicht: 37 kDa

Gen-ID: 54984

NCBI Accession: NM_017884, NP_060354

UniProt: Q96BK5