ARFGAP1 Antikörper (Middle Region)

Produktnummer ABIN2787084

Produktdetails anti-ARFGAP1 Antikörper

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GQPQSVTASS DKAFEDWLND DLGSYQGAQG NRYVGFGNTP PPQKKEDDFL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARFGAP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARFGAP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 406 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Andere Bezeichnung: ARFGAP1 (ARFGAP1 Produkte)

Synonyme: ARF1GAP antikoerper, HRIHFB2281 antikoerper, AI115377 antikoerper, Arf1gap antikoerper, Arf GAP1 antikoerper, arf1gap antikoerper, atfb1 antikoerper, atfb3 antikoerper, jlns1 antikoerper, k(v)7.1 antikoerper, kcna8 antikoerper, kcna9 antikoerper, kv1.9 antikoerper, kv7.1 antikoerper, kvlqt1 antikoerper, lqt antikoerper, lqt1 antikoerper, rws antikoerper, sqt2 antikoerper, wrs antikoerper, ARFGAP3 antikoerper, ADP ribosylation factor GTPase activating protein 1 antikoerper, ADP-ribosylation factor GTPase activating protein 1 antikoerper, ADP ribosylation factor GTPase activating protein 1 S homeolog antikoerper, putative ADP-ribosylation factor GTPase activating protein 1 antikoerper, ATP-dependent RNA helicase DBP9 antikoerper, ARFGAP1 antikoerper, Arfgap1 antikoerper, arfgap1.S antikoerper, Tb11.01.6060 antikoerper, arfgap1 antikoerper, LMJF_32_1230 antikoerper, MGYG_02419 antikoerper

Hintergrund: The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARF1GAP, HRIHFB2281, MGC39924
Protein Interaction Partner: KRTAP10-9, KRTAP9-2, KRTAP3-2, GABARAPL2, GRN, FOS, TRIM23, UBC, RPL22, HK1, RAD52, RPL11, RFC3, PRKACB, APOE, APOC3, APOB, ASB10, RASIP1, RAB23, COPS5, MED27, REEP5, APP, LRRK2, MAP1LC3B, TK1, SMN1, TMED2, CYTH2, COPA, CSNK1D, RGS2, KDELR1, ARF1,
Protein Size: 406

Molekulargewicht: 45 kDa

Gen-ID: 55738

NCBI Accession: NM_018209, NP_060679

UniProt: Q8N6T3

Pathways: p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response