ELP2 Antikörper (Middle Region)

Produktnummer ABIN2787102

Produktdetails anti-ELP2 Antikörper

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EESGVWLEQV RVGEVGGNTL GFYDCQFNED GSMIIAHAFH GALHLWKQNT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ELP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 826 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ELP2

Target: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Andere Bezeichnung: ELP2 (ELP2 Produkte)

Synonyme: zgc:153559 antikoerper, SHINC-2 antikoerper, STATIP1 antikoerper, StIP antikoerper, AU023723 antikoerper, Epl2 antikoerper, StIP1 antikoerper, Statip1 antikoerper, F14J22.24 antikoerper, elongator protein 2 antikoerper, elongator acetyltransferase complex subunit 2 antikoerper, elongator protein 2 antikoerper, elp2 antikoerper, ELP2 antikoerper, Elp2 antikoerper

Hintergrund: ELP2 regulates the ligand-dependent activation of STAT3. ELP2 acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Alias Symbols: FLJ10879, SHINC-2, STATIP1, StIP
Protein Interaction Partner: UBC, FAM96B, CIAO1, PAAF1, WRNIP1, ELP3, NRBP1, CD2AP, KIAA1033, USP34, SNRPB2, PRPSAP2, KIF5B, MMS19, IKBKAP, ELP4, CTDP1, STAT5B, STAT1, JAK2, JAK1, STAT3, TYK2,
Protein Size: 826

Molekulargewicht: 92 kDa

Gen-ID: 55250

NCBI Accession: NM_018255, NP_060725

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus