Pellino 1 Antikörper (N-Term)
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- Target Alle Pellino 1 (PELI1) Antikörper anzeigen
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Pellino 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ESPIDFVVTD TVPGSQSNSD TQSVQSTISR FACRIICERN PPFTARIYAA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PELI1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PELI1
- Top Product
- Discover our top product PELI1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 418 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
- Andere Bezeichnung
- PELI1 (PELI1 Produkte)
- Synonyme
- 2810468L03Rik antikoerper, A930031K15Rik antikoerper, AA409794 antikoerper, AI586297 antikoerper, D11Ertd676e antikoerper, peli1 antikoerper, peli1.L antikoerper, pellino1 antikoerper, xpellino1 antikoerper, wu:fd12d01 antikoerper, zgc:153297 antikoerper, pellino E3 ubiquitin protein ligase 1 antikoerper, pellino 1 antikoerper, pellino E3 ubiquitin protein ligase 1 S homeolog antikoerper, pellino E3 ubiquitin protein ligase 1b antikoerper, PELI1 antikoerper, Peli1 antikoerper, peli1.S antikoerper, peli1b antikoerper
- Hintergrund
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PELI1 is an scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. PELI1 is required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
Alias Symbols: DKFZp686C18116, MGC50990
Protein Interaction Partner: UBC, VAC14, TRIP13, BCL6, SRPK2, SRPK1, DEAF1, IRAK1, UBE2V1, UBE2N, UBE2D2, UBE2D1, IRAK4, TRAF6, NR2C2, MYD88, SMAD6, IL1R1, TBK1, IKBKB, UBE2I, RIPK1, IRAK2,
Protein Size: 418 - Molekulargewicht
- 46 kDa
- Gen-ID
- 57162
- NCBI Accession
- NM_020651, NP_065702
- UniProt
- Q8C669
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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