GBA3 Antikörper (N-Term)

Produktnummer ABIN2787250

Produktdetails anti-GBA3 Antikörper

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Bindungsspezifität: N-Term

Reaktivität: Human, Hund, Pferd, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GBA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GBA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 469 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: GBA3 (GBA3 Produkte)

Synonyme: im:6912508 antikoerper, CBG antikoerper, CBGL1 antikoerper, GLUC antikoerper, KLRP antikoerper, glucosylceramidase beta 3 antikoerper, glucosidase, beta, acid 3 (gene/pseudogene) antikoerper, glucosidase, beta, acid 3 (cytosolic) antikoerper, cytosolic beta-glucosidase antikoerper, glucosylceramidase beta 3 (gene/pseudogene) antikoerper, Gba3 antikoerper, gba3 antikoerper, GBA3 antikoerper, LOC100344458 antikoerper

Hintergrund: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).
Alias Symbols: CBGL1, GLUC, KLrP, MGC104276, MGC126878
Protein Interaction Partner: PRKCSH, UBC,
Protein Size: 469

Molekulargewicht: 54 kDa

Gen-ID: 57733

NCBI Accession: NM_020973, NP_066024

UniProt: Q9H227