TMPRSS3 Antikörper (N-Term)
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- Target Alle TMPRSS3 Antikörper anzeigen
- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Rind (Kuh), Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TMPRSS3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TMPRSS3. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS3
- Top Product
- Discover our top product TMPRSS3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 344 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).
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Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).
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- Target
- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
- Andere Bezeichnung
- TMPRSS3 (TMPRSS3 Produkte)
- Synonyme
- TMPRSS3 antikoerper, DKFZp469L1528 antikoerper, DFNB10 antikoerper, DFNB8 antikoerper, ECHOS1 antikoerper, TADG12 antikoerper, transmembrane protease, serine 3 antikoerper, TMPRSS3 antikoerper, Tmprss3 antikoerper
- Hintergrund
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This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Alias Symbols: DFNB10, DFNB8, ECHOS1, TADG12
Protein Interaction Partner: TMED7, UBC, RXRA, EEF1A1,
Protein Size: 344 - Molekulargewicht
- 37 kDa
- Gen-ID
- 64699
- NCBI Accession
- NM_032405, NP_115781
- UniProt
- Q8WY52
- Pathways
- Sensory Perception of Sound
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