PLAT Antikörper (Middle Region)
-
- Target Alle PLAT Antikörper anzeigen
- PLAT (Plasminogen Activator, Tissue (PLAT))
-
Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Schwein, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Pferd
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PLAT Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- TVILGRTYRV VPGEEEQKFE VEKYIVHKEF DDDTYDNDIA LLQLKSDSSR
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 82%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PLAT. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PLAT
- Top Product
- Discover our top product PLAT Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 516 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- PLAT (Plasminogen Activator, Tissue (PLAT))
- Andere Bezeichnung
- PLAT (PLAT Produkte)
- Synonyme
- T-PA antikoerper, TPA antikoerper, AU020998 antikoerper, AW212668 antikoerper, D8Ertd2e antikoerper, tPA antikoerper, PATISS antikoerper, tpa antikoerper, Plat antikoerper, plat antikoerper, t-pa antikoerper, plasminogen activator, tissue type antikoerper, plasminogen activator, tissue antikoerper, chromosome 20 open reading frame 181 antikoerper, plasminogen activator, tissue L homeolog antikoerper, PLAT antikoerper, Plat antikoerper, plat antikoerper, C20orf181 antikoerper, plat.L antikoerper
- Hintergrund
-
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: DKFZp686I03148, T-PA, TPA
Protein Interaction Partner: PDGFC, POT1, TERF2, CKAP4, LRP1B, GRIN1, SERPING1, SERPINI1, SERPINA5, MAPK3, LAMA3, F10, PLAU, CLEC3B, SPARC, MAPK1, PLAT, SERPINE1, PLG, HMGB1, ANXA2, LAMA1, KRT8, FGA, CALR, LRP1, FN1, LAMA5, F2,
Protein Size: 516 - Molekulargewicht
- 53 kDa
- Gen-ID
- 5327
- NCBI Accession
- NM_033011, NP_127509
- Pathways
- Autophagie, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interaktom
-