ASAH1 Antikörper (N-Term)
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- Target Alle ASAH1 Antikörper anzeigen
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ASAH1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MPGRSCVALV LLAAAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ASAH1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ASAH1
- Top Product
- Discover our top product ASAH1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 395 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).
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Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
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- Target
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
- Andere Bezeichnung
- ASAH1 (ASAH1 Produkte)
- Synonyme
- AC antikoerper, ACDase antikoerper, ASAH antikoerper, PHP antikoerper, PHP32 antikoerper, SMAPME antikoerper, 2310081N20Rik antikoerper, Asah antikoerper, MGC82286 antikoerper, asah1 antikoerper, zgc:101637 antikoerper, ASAH1 antikoerper, zgc:66026 antikoerper, N-acylsphingosine amidohydrolase 1 antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1 antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1a antikoerper, Acid ceramidase antikoerper, N-acylsphingosine amidohydrolase (acid ceramidase) 1b antikoerper, ASAH1 antikoerper, Asah1 antikoerper, asah1.L antikoerper, asah1a antikoerper, asah-1 antikoerper, asah1b antikoerper
- Hintergrund
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This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into
Alias Symbols: AC, ASAH, FLJ21558, FLJ22079, PHP, PHP32, ACDase
Protein Interaction Partner: SRPK1, CAMK1D, FBXO6, UBC, PSMA3, Bub1b, TSC22D1, SETDB1, SMPD1,
Protein Size: 395 - Molekulargewicht
- 44 kDa
- Gen-ID
- 427
- NCBI Accession
- NM_177924, NP_808592
- UniProt
- Q13510
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