GCFC2 Antikörper (N-Term)

Produktnummer ABIN2787542

Produktdetails anti-GCFC2 Antikörper

Target: GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCFC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SEPDDHEKRI PFTLRPQTLR QRMAEESISR NEETSEESQE DEKQDTWEQQ

Homologie: Cow: 79%, Dog: 100%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 83%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against C2orf3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C2orf3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 781 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GCFC2

Target: GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))

Andere Bezeichnung: C2orf3 (GCFC2 Produkte)

Synonyme: C2orf3 antikoerper, DNABF antikoerper, GCF antikoerper, TCF9 antikoerper, A130099G21 antikoerper, AW146020 antikoerper, GCF2 antikoerper, Tcf9 antikoerper, C11H2orf3 antikoerper, RGD1304792 antikoerper, C17H2orf3 antikoerper, zgc:171819 antikoerper, GC-rich sequence DNA-binding factor 2 antikoerper, GC-rich sequence DNA binding factor 2 antikoerper, GCFC2 antikoerper, Gcfc2 antikoerper, gcfc2 antikoerper

Hintergrund: The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Alias Symbols: DNABF, GCF, TCF9, C2orf3
Protein Interaction Partner: HDAC11, CREB3L2, ATXN1, SUMO2,
Protein Size: 781

Molekulargewicht: 89 kDa

Gen-ID: 6936

NCBI Accession: NM_003203, NP_003194

UniProt: P16383