Vitronectin Antikörper (N-Term)

Produktnummer ABIN2787545

Produktdetails anti-Vitronectin Antikörper

Target: Vitronectin (VTN)

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vitronectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EDEYTVYDDG EEKNNATVHE QVGGPSLTSD LQAQSKGNPE QTPVLKPEEE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against VTN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VTN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 478 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Vitronectin

Target: Vitronectin (VTN)

Andere Bezeichnung: VTN (VTN Produkte)

Hintergrund: VTN is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: V75, VN, VNT
Protein Interaction Partner: GOPC, EED, ADH5, RHOXF1, ADTRP, ETV7, RPL13A, CBX1, PRDX4, CRADD, SIX1, GLUD1, CKS2, CD247, PRKCA, PRKACA, RBM25, WDR18, PRPF40A, SMU1, LUC7L3, SF3B6, HP1BP3, PRPF19, PHGDH, SF3B1, SF3B3, SRSF10, USP39, PRPF8, SF3A1, SAP18, HNRNPR, RBM39, SRSF11, BUD31, D
Protein Size: 478

Molekulargewicht: 52 kDa

Gen-ID: 7448

NCBI Accession: NM_000638, NP_000629

UniProt: P04004

Pathways: Autophagie, Smooth Muscle Cell Migration